Hey, So, I recently came across this astounding fact regarding stem cells while reading up on several health-related topics.

You know those tiny but powerful cells within our bodies?

As it happens, researchers have been experimenting with them to produce cardiac muscle cells in the lab. It's similar to having a shield against cardiac problems!

They therefore utilize a variety of stem cell types, some derived from embryos, some from normal adult cells, and some that are already present in our hearts.

These cardiac muscle cells intervene to repair the heart when necessary, acting as superheroes. Scientists are putting a lot of effort into ensuring the efficacy and safety of this medication.

Who knows? For those with heart issues, it might be a game-changer, extending their lives and improving their quality of life.

Relationship b/w CVDs & Stem cell Therapy

Cardiovascular disease (CVD) is a leading cause of global mortality, with myocardial infarction (MI) being the most significant contributor.

Heart failure (HF) is a terminal complication of CVD, often worsened by chronic inflammation.

A major obstacle to finding effective treatments, despite advancements in medical interventions, is the adult heart's limited ability for regeneration.

Cardiomyocytes produced from stem cells have shown great promise in the field of cardiac regeneration, with the ability to repair damaged myocardium and improve heart function.

After a heart attack, limited cardiomyocyte regeneration leads to scar tissue formation.

Stem cell therapy aims to replace damaged tissue, but current approaches have shown limited success due to low cell survival and differentiation. 

Differentiated cardiomyocytes from pluripotent stem cells (pSCs) offer better engraftment and functional improvement.

Pericardial stem cells, activated by inflammation, show promise in heart repair. Transcriptional analysis identifies myoblast determination protein 1 (MyoD) as a key regulator of myogenic progression.

Cardiac-committed pSCs demonstrate long-term engraftment, suggesting their potential for effective cardiac regeneration therapy.

Human cells obtained from skin biopsies, blood draws, urine samples, or hair follicles can be reprogrammed into,

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